The aim of this research is to develop and investigate a model that examines the mediating role of job embeddedness in the relationships among high-performance work practices, creative performance and talented employee retention at Egyptian travel agents. Using a questionnaire, data were collected from 398 employees working at the Egyptian travel agents category A. To test the relationships among the study variables, the data were analyzed via LISREL 8.30 through structural equation modeling. The results revealed that the implementation of high-performance work practices (HPWPs) enhances job embeddedness (JE) of Egyptian travel agents' employees. JE, in return, leads to high levels of creative performance(CP) and talented employee retention (TRT). The results also proved that JE partially mediate the relationships between HPWP, CP and TRT at the Egyptian travel agents.