The research aimed to identify the attitudes of the students of the Faculty of Agriculture in Cairo, Al Azhar University towards self-employment, and to determine the significance of the relationship between some independent variables of the respondents and their attitudes towards self-employment. This research was conducted on final year students at the Faculty of Agriculture in Cairo, Al Azhar University, and data were collected from a sample of students amounting to 200 respondents by a questionnaire through personal interview with the respondents, during the months of April and May 2021. rFequencies, percentages, the weighted average, Pearson's simple correlation coefficient, and chi-square were used in data analysis. The most important results of the search were as follows: More than two thirds of the respondents (68%) did not receive training courses in the field of self-employment. Half of the respondents (50%) who received training courses their benefit degree from these courses were medium. Nearly half of the respondents (48%) fall into the low-income category. More than half of the respondents' (50.5%) parents are self-employed. Over two-thirds of them (67.5%), their families do not own small businesses. More than three-fifths of the respondents (61.5%) do not prefer self-employment related to animal production projects. A slightly less percentage, (61%) of them do not prefer self-employment related to plant production, and those who prefer self-employment related to food manufacturing projects are (53%). More than two-fifths of the respondents (43%) have a positive attitude towards self-employment. There is a positive significant relationship at the 0.01 level between the variables of receiving training courses on self-employment, working during the summer vacation, family ownership of small businesses, and the respondents' attitude towards self-employment in general. There is a positive correlation at the 0.01 level between the variables of family income, the level of ambition, and the respondents' attitude towards self-employment in general.