Rice maternal lines along for better combining abilities run an effective instrument for increasing rice manufacture. In this study, twenty-four combinations of four female and six male lines began by applying a line × tester mating design. Two different water regimes: regular irrigation and water stress were used to test crosses and their maternal lines. In general, water deficit had a significant impact on yield component characteristics and was regulated by non-additive gene action. As it should have been, the non-additive effects played a big role in the grain yield (GY). The parental line Giza 178 and Sk104 were registered as the best combiners for GY under both conditions. The crosses combinations G.178 × N22, SK107 × IRAT112 and SK104 × AZUCENA showed considerably favorable SCA effects on grain yield. In general, the results of this study revealed that the GCA and SCA are important for the understanding of the genetic components and gene actions of rice yield attributes. As a result, we confirmed the importance of taking these findings into account when selecting superior parents for developing superior hybrid under the water-stress conditions in rice.