Field experiments were conducted in a private farm in Ashmon district, Menoufia Government to evaluate the efficacy of four chemical fungicides and two biofungicides against tomato early blight disease under field conditions during the two consecutive seasons (2018-2019 and 2019-2020). The tested fungicides were, Amistar 25% SC (azoxystrobin), Anadol 80% WP (mancozeb), Ridomil Gold MZ 68% WP (metalaxyl M – mancozeb) and Score 25% SC (difenoconazole) at two rates each (25 and 50 cm³, 125 and 250 gm, 100 and 200 gm and 25 and 50 cm³, 100L^-1, respectively) and the two biofungicides were (Bio Arc 6% WP (Bacillus megaterium), and Plant guard (30 million cell ml^-1) (Trichoderma harzianum) at two rates each (125 and 250 gm, 100L^-1, respectively). Each chemical fungicide and biofungicide was applied at recommended and half recommended rates as foliar spraying 3 times season^-1. The results clearly indicated that, chemical fungicides were significantly more effective than the biofungicides, and all the tested compounds particularly Score, 25%, SC Amistar 25% SC and Ridomil Gold MZ 68% WP significantly reduced incidence and severity of early blight disease in tomato and subsequently increase a tomato fruit yields in comparison with the untreated control. Also, Plant guard was more effective than Bio Arc. Regardless the examined fungicide, and as expected, the higher rate of application higher reduction of the tomato early blight disease, and subsequently higher fruit yield.