Sorghum bicolor L. Moench, also known as sweet sorghum, is a sugar-based biofuel crop that grows in tropical climates. Although the majority of sweet sorghum cultivars are open-pollinated, hybrids may provide yield and seed production benefits. The study was to look at the performance of F1 sweet sorghum hybrids and their parents, as well as their agronomic traits, heterosis, heritability, inbreeding depression, and genetic advancement. GR Coba, AG SC2, AG SC3, and Brandes were used in this study as parents of sweet sorghum crosses. The mean Performance of all morphological traits including (stalk weight and stripped stalk weight) and the technological traits (Juice extraction, sucrose, purity and reducing sugar percentage) in addition to, yield traits (juice and ethanol yields/fed.). All crosses showed a significant difference among the evaluated different populations. For four traits in the three crosses (i.e stalk weight, stripped stalk weight, sucrose and reducing sugar) were used to determined heterosis, inbreeding depression, broad sense heritability and genetic advance, the dominant genetic variance in stalk weight, stripped stalk weight and sucrose percentage were high in the additive genetic variance except reducing sugar percentage trait was high in the dominance genetic variance. To summarize, the results of this study show that the third cross performbest cross in ethanol production.