The goal of the present study is to investigate the effect of explosion puffing and convection air drying on the physical, chemical and sensory properties of dried seedless grape, and cost of operation. The obtained results showed that, the drying rate of puff drying method (PD) was faster than that of convection air drying method at the corresponding drying condition of (60°C and 1.5 m/s air velocity). The seedless grape samples dried by PD were the best for the most of physico-chemical quality properties such as color index, texture, rehydration ratio, and shrinkage rate compared to similar samples dried by AD that required a longer time. The seedless grape dried by PD method had the highest amount of total phenolic compounds (276.73 mg/100g DM) than that in convection air drying. The highest value of total carotenoids (84.44 mg/100g DM) was found in seedless grape dried by PD method. The PD drying process lead to retention of total flavonoids in dried seedless grape samples at a wide rate depending on the drying time compared to the AD drying methods. The PD technique exhibited the ability to obviously quench the DPPH radical compared to the AD method. In conclusion, the seedless grape samples dried by PD exhibited good sensory properties and better acceptability. PD can meet the four major requirements in drying foods: short time of operation, energy efficiency, cost of operation, and quality of dried products which indicates that puff drying is a good choice for grape processing.