Root rot and wilt diseases are widespread in Egypt causing severe yield losses on marigold (Calendula officinalis L.) plants. These diseases were detected in Beni-sweif governorate during surveying trials in 2017/2018 and 2018/2019 seasons. The isolated fungi were Fusarium subglutinans, F. oxysporum, F. solani, F.semitectum, F.nivale, F.roseum, Rhizoctonia solani, F. nivale and Pythium splendens which achieved the highest occurrence percentage in isolation trials from samples of Beni- sweif governorate. Fusarium. oxysporum was more virulent than the other fungi in pathogenicity tests on marigold. The effect of garlic and onion watery extracts , microelements,macroelements, Ascopine, Potasien, yeast ( Saccharomyces cerevisiae) and fungicides on marigold root rot and wilt diseases incidence were tested under in vitro and in vivo. These controlling agents, however, were varied in their positive efficiency against diseases. Fungicides were the superior treatments in controlling diseases and improving plant growth parameters. In the applied field experiments, all treatments tested significantly decreased the percentages of infection and increased the growth parameters compared with control treatment.