The objective of this research is to study the impact of real interest rate, Net domestic credit and government expenditure changes on the Egyptian economy. Using the Ordinary Least Squares (OLS) method, the results showed that the expansion of domestic debt in Egypt in the period under study (1976-2018) has a positive and significant impact on economic growth. The study recommends that the government should encourage Net Domestic Credit, provided that the funds are used in productive economic means. Net Domestic credit plays an important role in the growth of developed and emerging market economies.