Objective: aiming to evaluate stress distribution in addition to compare different types of low-profile attachments for implant-retained mandibular overdenture. Objective: aiming to evaluate stress distribution in addition to compare different types of low-profile attachments for implant-retained mandibular overdenture. Materials and methods: The present study a simulated mandible the two attachments were examined after application of vertical and oblique 45° loads on the region of the premolar/molar. The results show Equators received less Von Mises stress than locators by about 40% under vertical loading. On the other hand, under oblique loading locators showed better performance and less Von Mises stress by about 10%. Conclusions: Equator attachment can be considered equivalent to locator attachment, while it may have better performance in certain situations. Tilting the applied load from vertical to oblique load dramatically increase the total deformation and Von Mises stress. Bone (cortical and spongy) and mucosa showed similar (equivalent) behavior under Equators and Locators attachments. Using equator attachments generated slightly less stresses on over-denture while using locators transfer less stresses to implants body and flexible caps.