In this study a total of 14 infected sheep and 6 lactating albino goats were used. These animals were proved to be brucellosis seropositive using TAT, MET, BAPAT, RBPT and rivanol test as well as bacteriologically positive by isolation of Brucella melitensis biovar 3 from their milk. These animals were subjected to trials of treatment using three different methods. Goats treated by antibiotics combined with BCG showed the highest recovery rate (on bacteriological basis), followed by animals treated with antibiotics only and finally animals treated with antibiotics combined ID. The recovered treated animals were placed under careful investigation for 2 years with no evidence of Brucella infection neither in them nor in their newborns.