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77845

Evaluation of bivalent inactivated oil adjuvant African Horse Sickness vaccine in Guinea pigs and mice

Article

Last updated: 04 Jan 2025

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Subjects

-

Tags

Veterinary microbiology and pathobiology (Veterinary Bacteriology & my…irology, immunology, parasitology, pathology, and molecular biology).

Abstract

In this study, neutralizing antibody response in Guinea pigs and mice inoculated by African horse sickness (AHS) bivalent inactivated oil adjuvant vaccine was similar when compared serologically with that in horse. Therefore, using G. pigs and mice may be a method of great value in potency test for routine immunization. Potency test of the prepared vaccine using an immunization challenge protocol in adult mice was studied, using challenge virus with 100, 50 and 25 LD50. The highest protection level (95%) was with the dilution of 50 LD50/0.05 ml

DOI

10.21608/jvmr.2008.77845

Keywords

Evaluation, bivalent, inactivated, oil, African, Horse, Sickness, vaccine, pigs, Mice, Guinea

Authors

First Name

Nashwa K.

Last Name

Madkour

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

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City

-

Orcid

-

First Name

S. K.

Last Name

Rofaiil.

MiddleName

-

Affiliation

Veterinary Serum and Vaccine Research Institute, Abbasia, Cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

18

Article Issue

1

Related Issue

11635

Issue Date

2008-03-01

Receive Date

2020-03-17

Publish Date

2008-03-01

Page Start

57

Page End

61

Print ISSN

2357-0512

Online ISSN

2357-0520

Article File

JVMR_Volume 18_Issue 1_Pages 57-61.pdf

PDF . 174.9kB

Link

https://jvmr.journals.ekb.eg/article_77845.html

Detail API

https://jvmr.journals.ekb.eg/service?article_code=77845

Order

9

Type

Original Article

Type Code

891

Publication Type

Journal

Publication Title

Journal of Veterinary Medical Research

Publication Link

https://jvmr.journals.ekb.eg/

MainTitle

Evaluation of bivalent inactivated oil adjuvant African Horse Sickness vaccine in Guinea pigs and mice

Details

Type

Article

Created At

22 Jan 2023