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77698

Ethological Problems and Learning Disability due to Aluminium Toxicity in Rats

Article

Last updated: 22 Jan 2023

Subjects

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Tags

Veterinary basic research (Veterinary Histology, anatomy, physiology, biochemistry, animal behavior, and animal nutrition).

Abstract

A total of 35 Sprague-Dawley adult rats were used to investigate the effect of aluminium toxicity on behavioural patterns of adult female rats and learning ability of offspring. Rats were allotted into 4 groups, group one received 2g/l anhydrous aluminium chloride (n=10), group two received 3g/l anhydrous aluminium chloride (n=10), group three received 3.5g/l anhydrous aluminium chloride in drinking water (n=10) and control group did not receive anhydrous aluminium chloride (n=5) from 8th day of pregnancy till weaning of pups. The obtained results showed that feeding time increased significantly in 2g/l and 3.5g/l anhydrous aluminium chloride groups than control one, while, litter licking frequency and nursing time increased significantly in 2g/l anhydrous aluminium chloride than other groups. On contrary
lying time decreased significantly in rats treated with 2g/l anhydrous aluminium chloride than other groups, licking and scratching decreased in 3g/l and 3.5g/l anhydrous aluminium chloride groups. In considering, the time spent in closed arms by offspring pups exhibited much times significantly than control group, while, time spent in open arms of elevated plus maze decreased significantly in all treated groups than control group. On the other hand, number of entries in open arms significantly decreased in treated groups than control one.

DOI

10.21608/jvmr.2013.77698

Keywords

Ethological, Problems, Learning due, Disability, aluminium, toxicity, Rats

Authors

First Name

Amira,

Last Name

A. Goma

MiddleName

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Affiliation

Department of Animal Husbandry and wealth development, Faculty of Veterinary Medicine, Alexandria University, Egypt

Email

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City

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Orcid

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First Name

U. E.

Last Name

Mahrous

MiddleName

-

Affiliation

Department of Animal Husbandry and wealth development, Faculty of Veterinary Medicine, Damanhour University, Egypt

Email

-

City

-

Orcid

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Volume

22

Article Issue

1

Related Issue

11611

Issue Date

2013-03-01

Receive Date

2020-03-17

Publish Date

2013-03-01

Page Start

154

Page End

159

Print ISSN

2357-0512

Online ISSN

2357-0520

Link

https://jvmr.journals.ekb.eg/article_77698.html

Detail API

https://jvmr.journals.ekb.eg/service?article_code=77698

Order

24

Type

Original Article

Type Code

891

Publication Type

Journal

Publication Title

Journal of Veterinary Medical Research

Publication Link

https://jvmr.journals.ekb.eg/

MainTitle

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Details

Type

Article

Created At

22 Jan 2023