To study the effect of silicon application on P-Zn interaction in sandy soils and their effects on the growth of wheat, a pot experiment was conducted in greenhouse with wheat, Triticum aestivum L. variety Sahel 1. Phosphorus was applied as Super phosphate 15.5% P₂O₅ at rates of 0, 50 and 100 Kg P/feddan and zinc as ZnSO₄.7H₂O at rates of 0, 10 and 20 Kg Zn/feddan. Silicon was added as Na₂SiO₃.5H₂O at rates of 0 and 300 Kg Si/feddan. The results showed that dry matter yield was significantly higher with Si-treated soil than with Si-untreated soil. Application of 50 Kg P/feddan, significantly increased the dry matter yield of wheat over control while the rate of 100 Kp/feddan caused a decrease in the dry matter yield over 50 Kg P/feddan, in both Si-treated and untreated soil. In both cases also, zinc application at the rate of 20 kg/feddan increased dry matter yield especially at the rates of 0 and 50 kg P/feddan. The concentrations and uptake of P and Zn increased with the application of P and Zn, respectively. Zn concentration was decreased by increasing both levels of P. Silicon concentration in plant was decreased by raising rate of P from 0 to 50 or 100 kg/feddan, on the other hand, it  was  a slightly increased with 20 Kg Zn/feddan. The uptake of Si and Zn by wheat plant was higher with Si-treated soil than untreated soil. These results give evidence of the beneficial effect of silicon element on the P-Zn interaction and growth of wheat in sandy soils.