The present investigation was carried out to study the effect of feeding with diet
supplemented with coriander and cumin in either powder or essential oil form with or
without turmeric on hypercholesterolemic rats for 45 days. Data emphasized that rats
given different experimental diets exhibited significant decrement in serum total
cholesterol and low density lipoprotein compared with a group of rats given
hypercholesterolemic diet while the level of high density lipoprotein was increased
during experimental period. Also, feeding with diets supplemented with coriander
essential oil (0.05%) or powder (11%) with or without turmeric (0.25%) from the diet
were responsible for decreasing serum triglycerides while cumin powder (5%) as well
as essential oil (0.07%) had lower activity in this concern. Likewise, both serum
creatinine and uric acid (kidney function) were decreased as a result of feeding with
all tested spices. The sameness result was recorded for either AL T or AST (liver
function enzymes). Concerning serum glucose, results ascertained that dietary
coriander and cumin in powder form or essential oil with or without turmeric decreased
serum glucose compared with that of rats fed with hypercholesterolemic diet. It could
be concluded that, remarkable beneficial could be obtained by using these spices in
their powder or essential oil forms especially in hypercholesterolemic case.