The present study was conducted to investigate the accumulation of some heavy metals (Cd, Cu, Pb and Zn) in soils and plants with different sources of  pollution. The soil samples were collected from 3 sites from each of  El-Gabal EL-Asfar, Abou-Rawash, and Helwan areas which received sewage sludge and sewage effluent for a long time. Also, one soil sample from Helwan was collected to represent the contamination by industrial waste.The plant samples were taken from the same location of soil samples. Soil pH and total carbonate content (TCC) are slightly decreased as the irrigation period increased. However, organic matter increased. Total, bioavailable contents of Cd, Cu, Pb, and Zn of soils, increased as the irrigation period increased. Total contents exceeded, in many cases, and/ or reached, in some ones, the maximum permitted loadings. DTPA-extractable Cd, Cu, Pb and Zn increased continuously in the studied areas which received sewage sludge, sewage effluent and industrial materials for a long time. Bioavailable portions were found to represent a great deal of the total contents. The low percentage of total extracted by DTPA is due to its precipitation as CaCO₃. These results give an evidence of high availability of sewage effluent burden-metals to plants. There are negative correlation confections between DTPA extractable -Cd and each of pH and  CaCO₃; and a positive correlation confections with total, organic matter and clay contents. The concentrations of Cd, Cu, Pb and Zn in different plant organs increased with increasing the irrigation time period of sewage effluent and both sewage sludge and industrial material applications to soils. The absolute values of  these metals in plant organs are different from metal to another, depending on the sewage sludge content and the  availability of these metals in the soil which are controlled by different soil parameters (CaCO₃, pH, clay and organic matter). The values of these metals followed the order Cd < Pb < Cu < Zn. The obtained results indicate that the heavy metals accumulation in  leaves or straw higher than edible parts (grains or seeds) of plants. This is due to the low translocations of these metals in plants.