This study deals  with the relationship between soil properties and the specific adsorption of manganese and cadmiumin some  soils of the north eastern Nile Delta region . This work was conducted on seven  different soil profiles of heavy clay soil texture.   To achieve this goal, a detailed study was conducted on the most important physical and chemical properties of the collected soil samples, then a quantitative specific adsorption experiment was carried out.The specific adsorption of manganese and cadmiumions in the presence of sodium.as a monovalent cation and calcium as a divalent cation and as shown on that the higher the added concentration, the higher the specific adsorption as shown by the straight line equation on for manganese and cadmium, while the role of Sodium as a single cation helps the adsorption of manganese and cadmiumin the superficial layers rather than the sub-surface layers due to the presence of organic matter and clay content. In the presence of calcium, the specific adsorption of manganese and cadmiumdecreased, as calcium occupies all exchange sites on the adsorption complex as a binary cation. However in the presence of calcium The adsorption increased in the surface layers than in the sub-surface layers due to the presence of organic matter and clay content in the surface layer than the sub-surface layer.