Currently, the Egyptian government is working hard to encourage and motivate citizens to reclamation the desert soils. So, a pot experiment was carried out aiming at evaluating the effect of some organic fertilizers as main factor i.e., compost, chicken manure and town refuse at different rates (0.0, 10.0 and 15.0 Mg fed^-1) as sub main factor as well as bentonite  amendment at different rates (0.0, 10.0 and 15.0 Mg fed^-1) as sub-sub main factor on the performance of lettuce  plants grown on sandy soil. Lettuce growth criteria i.e., plant height, plant fresh and dry weights, head diameter and root length as well as concentrations of nutrients i.e., N, P, K, Fe and Mn in plant tissues were measured at harvest stage. The main results showed that the lettuce plants treated with compost had the highest values of all aforementioned traits followed by that treated with chicken manure, while lettuce plants treated with town refuse possessed the lowest values.  Also, the values of all aforementioned traits increased as the added rate of the studied organic amendment increased. On the other hand, the soil addition of bentonite had a positive effect on lettuce plant performance compared to the corresponding plants grown without soil addition of bentonite (control treatment), where the values of all aforementioned traits increased as the added rate of the bentonite amendment increased.  It can be concluded that soil addition of organic manures in combining with bentonite amendment represents an attractive option for programs of fertilization under the sandy soil.