The effect of sprinkler irrigation management on barley yield, soil moisture distribution and water use efficiency was studied under field conditions. A field experiment was conducted in 2005/2006 growing season in sandy loam soil, at Wadii-Ghepeen (Bani-Waleid Governorate, Libya),. A drought-tolerant genotype of barley (Hordeum vulgare L.: AKSAD 67) was irrigated by semi-portable sprinkler irrigation system with a local well-water (electrical conductivity of 2.7 dS m^-1). The experiment included two factors: The frist factor was two levels of sprinkler distance: 12 and 6 m, and the second factor was two levels of working hours: 2 and 3 h. The control treatment was that recomended in the region (i. e. 12 m sprinkler distance and 5 working hours). So, the experiment consisted of five treatments, namely: 12 m × 3 h.; 6 m × 3 h.; 12 m × 2 h.; 6 m × 2 h. and 12 m × 5 h., labeled as A, B, C, D and Co, respectively. To evaluate the performance of the sprinkler system and yield response to different treatments, many field measurements were achieved: local rainfall; sprinkler discharge (under working pressure of 2 bar); uniformity coefficient; total dry matter ; grain yield and water use efficiency. Also, change of soil moisture contents; seed germination percent and crude protin- were determined. The main results can be summarized as follows: in general, the results indicated that both total dry and grain yields were increased as irrigation water amount decreased. The lowest water ammount was consumed under C treatment, therefore, appeared the highest water use efficiency.The statistic analsys shown that, there was no significant effect between sprinkler distances, while significant and high significant effect were found in both working hours and the interaction of sprinkler distance and working hours, respectively. The results indicate that maximum uniformity coefficient was found under 6 m treatments (i. e. B and D treatments). Germination test showed that, there was no observed effect as difference among all treatments. Following of soil moisture changes after irrigation, indicated that, it is not necessary to bring up soil moisture content to 100% of soil field capacity, while 50% of soil field capacity was found to be optimum amount for high yield production. Such irrigation water quality can be safely used, where the precipitation can prevents salt accumulation hazard.