Two lisimeters experiments were conducted at Sakha Agric Res. Station from during the two successive winter seasons of 2005/2006 and 2006/2007 to study the effect of amino acids application on wheat crop tolerance to salinity. Split plot design was used the main plots were assigned by five levels of irrigation water salinity of 0.4, 2, 4, 6 and 8 dSm^-1. The sub plots were assigned by four methods of amino acids applications of control (without application), soaking wheat grains, foliar application and soaking + foliar application. The amino acids used are mixture of proline, Arginine and Glutamic, 10 ppm from each one. The results of the present work can be summarized as follows:                 Content of proline and arginine in both grains and straw of wheat plant was increased with application of amino acids under all salinity levels. The values were higher with soaking of grains foliar application of amino acids in comparison with other treatments.                 Amount of arginine content in wheat grains and straw were increased by adding amino acids, but this increase was higher in the grains in comparison with those values in straw by soaking grains and foliar application treatment in the first and second growing seasons. The same trend was obtained in the straw. Increasing salinity levels increased amount of amino acids content by both grains and straw. The highest values were recorded under soaking grains + foliar application treatments where the highest values in grain are 195.8 and 107.0 mg/kg in the first and second growing seasons, respectively. The same trend was obtained in the straw.                 Data also, illustrated that values of osmotic pressure (O.P) in leaves were increased by adding amino acids, where the highest values were recorded with soaking of grains + foliar application of amino acids. The values are 9.95 and 12.02 atm. In the first and second growing seasons, respectively. Increasing salinity levels increased O.P values, where the highest values (13.90 and 12.32 atm) were recorded under 8 dS/m.