Two field trials on wheat (Triticum aestivum L.; Variety Misr1 ), were conducted at Tag El-Ezz Agricultural Research Station, Agricultural Research Centre (ARC), Dakahlia Governorate, Egypt during two successive winter seasons of 2016/17 and 2017/18. The experimental area were located at 30^o 95' 7034'' N latitude and 31^o 60' 0219' E longitude. The experiment treatments were included two factors 1) potassium humate (KH) at three levels (i.e. control, 3%, 6% of spraying solutions) and 2) proline (P) at three rates (i. e .control, 50, 100 mgl^-1). The two factors were layout in a split plot design with three replicates, where the potassium humate and proline treatments were located randomly in the main and sub plots, respectively.  The obtained results indicated that addition of potassium humate 6% with proline at 100 mgl^-1 gave the highest values of N, P and K % in wheat grains and straw, protein content and also gave the highest grains yield, compared with control treatment, so that the combined treatment of potassium humate 6% with proline 100 mgl^-1 was considered as most suitable treatment for obtaining the highest wheat yield under these experimental conditions. In addition to reduce the negative effects of salt stress on wheat plants.