Two field experiments were conducted during the successive two seasons of 2006/2007 and 2007/2008 to evaluate the effect of irrigation with saline water in combination with soils different in their soil properties (sandy clay loam and loamy sand ) on chemical properties of soil and  growth and  yield of wheat plant. Results concluded that, soil electrical conductivity and concentration of most cations  and anions were increased as a result of irrigation with saline water. The increase of soil EC was more pronounced in  sandy clay loam soil than in the loamy sand soil  in spite of that the two soils were irrigated with the same source of water. Also, results revealed that irrigation water salinity affected all wheat growth and yield parameters.