A factorial field experiment on wheat crop was conducted during two successive growth seasons of ( 2009/2010 ) ; ( 2010/2011 ) as two different On-farm trials sited in El-Dakahlia Governorate. The factors involved organic manuring from two biological treating composts of rates ( 0, 10 and 20 m³.fed ^-1 ) and NPKZn-mineral fertilization of the optimum recommended rates. The two experimental sites were clayey in texture have the average values of salinity index ECe ₌ 3.8 dS.m^-1 ; pH ₌ 7.8 and the available soil forms of N , P , K and Zn nutrients were : 30 , 19 , 600 , 0.6 ; respectively. The obtained results indicated the following points : 1- Such soils have to be manured with composts and fertilized with optimum recommended NPKZn-mineral fertilizers for obtaining higher wheat yields. 2- Grain and straw yields have been increased significantly as a result of adding organic manuring ( in forms of composts ). Higher wheat yields were realized by applying ( 10 or 20 m³.fed^-1 ) treatments. 3- The biological treated compost realized economically higher values of wheat yield relative to the untreated one. 4- The NPKZn- mineral fertilization with optimum recommended rates has increased the values of such wheat parameters. 5- The significant interaction effects of organic composting and NPKZn-mineral co-fertilization indicated that : the highest yield and its component were obtained  by applying the treatment of ( bio-treating compost of 10m³.fed.^-1 ). Along with optimum recommended rates of NPKZn mineral fertilizers.