Two Lyzimeter experiments were conducted at Sakha Agricultural Research Station, Kafr El-Sheikh, Egypt, for two seasons, 2010/2011 and 2011/2012 Lyzimeters (100 x 70 x 90 cm) were filled with clayey soil and irrigated with three water treatments since twenty three years ago.                 The present study aimed to investigate the effect of irrigation water quality for long-term on productivity of four barely   varieties (Giza123, 124, 126 and Giza129). Three irrigation water qualities; Nile water (W₁), polluted drainage water (W₃) and mixed water; W₂ ( 50% W₁ + 50% W₃) used for irrigation to study its effects on barely contents from four heavy metals Ni, Cd, Pb and Cu and some soil characteristics. A split–plot design with four replicates was used where, water treatments and varieties were allocated to main and sub-plots, respectively. The obtained results showed that: Using poor water quality for irrigation increased ECe, SAR, soluble cations and anions in soil paste extract and DTPA extractable heavy metals in soils (Cu, Ni, Cd and Pb) than that of mixed or good water quality. Highly significant differences of yield and yield components among barely varities were found due to irrigation water treatments and its contents of heavy metals.      Straw heavy metals content were higher than that of grains.  The results showed that Giza 123 was more tolerant variety to drainage and mixed water and its lower or higher contents of Ni, Pb and Cu. No significant differences were found among Cd content for all studied barley varieties. The heavy metals content of barley varieties from can be arranged as follow: With Pb: v₂< v₃ < v₁ 4 With Cu: v₁ < v₂ < v₃4 With Ni : v₂  < v₁ < v₃4