A pot experiment was conducted at Agric. station of Faculty of Agric. Mansura  University In 14 March; 2013 to study the effect of using some natural materials (phosphate rock and mineral sulfur ore) at two levels along with control treatment as fertilizers on eggplant growth, yield and some nutrients uptake. Split-split complete block design was used with three replicates. The main treatments (3treatments) represent the studied natural materials and the sub-main treatments were arranged for theirs levels (two levels more than control) of the natural materials used. The sub-sub main treatments were oriented for bacterial treatments (with and without bacterial inoculation). The two levels of natural material used were 1.5 and 3 g pot^-1 for each one and added to surface of soil and mixed with it before planting. Urea (46% N), superphosphate (15.5% P₂O₅) and potassium sulphate (50 % K₂O₅) fertilizers were applied at rates of 2.0; 1.5 and 0.5 g pot^-1, respectively (200 kg urea fed^-1,100 kg supper phosphate fed^-1 and potassium sulphate 50 kg fed^-1). Data revealed that application of some natural materials as fertilizers (phosphate rock and mineral sulfer ore) to soil due to increase some growth parameters (length, diameter, fresh weight and dry weight of eggplant), increased NPK % in whole plant  and fruit of eggplant, and increasedsome nutrient uptake both of eggplant at different periods and  eggplant fruit at two collections.