A field experiment was carried out at Kafr El-Hamam, Agricultural Research Station farm, Sharkia Governorate, Egypt, at lat. 30.35, long 31.30 and 13.00 m above the mean sea level during the two winter seasons, 2010/2011 and 2011/2012 to study the effect of different rates of inorganic NPK fertilizers i.e. 25, 50 and 75 % from the recommended dose (75, 15 and 24  kg N, P₂O₅ and K₂O /fed., respectively)  alone and/or companied with compost at the rate of 2 ton / fed., and/or  humic acid at 6 kg /fed, as a soil application on bread wheat productivity, chemical composition and economic evaluation. Results can be summarized as follows: Generally, in most cases, application of compost with 75 % from the recommendation dose of inorganic NPK fertilizers achieved significant increases in yield and its components as well as chemical composition of wheat plant. The addition of inorganic NPK fertilizers at the recommended rate alone led to the highest significant increases in all yield components and yield as well as macronutrient content of grain, straw and biological yield. Protein percentage was higher by using inorganic NPK fertilizers at the recommendation rate and /or application of compost with 75 % from recommendation dose of inorganic NPK fertilizers. Meanwhile, application of humic acid individually or companied with 25 and 50% from recommended dose of NPK fertilizer gave significant decrease in all parameters in this study. By Calculating the net return of wheat per Feddan, the highest net return is achieved by using the treatment 100% recommended dose (RD), which estimated about 6214 LE in the first season, 5549 LE in the second season. Using humic acid alone achieved the lowest net return about 3616 and 3443 LE in the first and second season, respectively.