Plants are likely to be affected by simultaneous boron (B) toxicity and salinity. Stresses on plants due to exposure to soils with high levels of naturally occurring salinity and boron, or due to irrigation with water containing high levels of salts and B can be done. For this reason, a greenhouse study was conducted at Soils Department, Faculty of Agriculture, Mansoura University in two different soils ( alluvial and sandy soil) during two successive summer seasons 2013 and 2014 to determine the interactive effects of salinity and varying concentrations of boron on growth, yield and ion relations of maize (Zea mays L.var.s.c.10). The experimental design was split plot with 3 replicates. Boron and salinity were applied with irrigation water. Boron levels were 0, 1, 2 and 3 mg L-1, while salinity levels were 0.4, 2.4, 4.4, 6.4, and 8.4 dSm−1. The average values of fresh and dry weight of shoot and root yield of maize (g/pot) as well as plant height (cm) during both seasons of 2013 and 2014 increased with increasing of B levels from 0 to 1ppm under S1 treatment (0.4 dSm−1), and then significantly decreased with any increasing in boron element under all different levels of irrigation water salinity for both soils under study. On the other hand, the average values of B concentration in maize plant for both seasons significantly decreased as salinity of irrigation water increase with constant of B level but it was significantly increase with increasing of B level and constant level of salinity in irrigation water. For example, the boron concentration in shoot were 28.75, 23.0, 19.1, 13.7 and 7.8 mg/kg ,respectively using irrigation water having EC 0.4,2.4,4.4,6.4 and 8.4 dSm-1,respectively and constant B concentration of 2 ppm, while the boron concentration of maize shoot were 0.9,15.65,23.0and 26.4mg/kg, respectively at using irrigation water having EC 2.4 dSm-1 and B concentration were zero,1,2 and 3 ppm , respectively . Also, the average values of nitrogen, phosphorus, potassium, sodium, chloride and calcium contents in maize were evaluated under the effect of different levels of boron and salinity in irrigation water at the same time.