At Agricultural Research Station Farm, Giza Governorate, Egypt, two field experiments were carried out during two successive winter seasons of 2013/2014 and 2014/2015 to study the effect of nitrogen (0, 90, 120 and 150 kg fed^-1.), potassium (0, 72 and 96 kg K₂O fed^-1) fertilizer rates and foliar application of boron in sthe form of H₃BO₃ (0 and 100 ppm) as well as their interactions on potato yield and its quality (Solanum tuberosum L.) cv. Spunta cultivar. A split-split-plot system in a randomized complete blocks design with three replicates was used in this respect. The obtained results indicated that significant increase in no. of tubers/plant, average tuber weight (g) and tuber yield was observed with 150 kg N fed^-1 over control. Increase in tuber yield with 96 kg K₂O fed^-1 was statistically significant compared to other treatments. The quality parameters like dry matter, specific gravity, total carbohydrate, reducing sugar and starch contents were improved with both nitrogen and K application. Spraying potato plants with boron at a rate of 100 ppm significantly increased yield and its components as well as quality of tubers. Interaction treatments among different rates of nitrogen, potassium fertilization and boron foliar application were significant on potato yield and quality. In general, the best interaction treatment among different rates of nitrogen, potassium fertilization and foliar application of boron was fertilization with 150 kg N fed^-1 in the form of ammonium sulphate, 96 kg K₂O fed^-1 in the form potassium sulphate and foliar application of boron to improve both yield and quality of potato crop as compared with other treatments.