Stevia (Stevia rebaudiana Bertoni) was recently introduced to Egyptian agriculture in order to produce a natural sweetener (Steviol glycosides ) instead of sugar (Sucrose) to cover some of the lack of sugar production, which reached annually about 0.8 million ton. So, a field experiment was carried out at Mallawi Agriculture Research Station , Minia Governorate , Egypt, during two successive seasons (2014 and 2015) to study the effect of different levels of mineral N fertilization and compost on yield and its quality of stevia (Stevia rebaudiana Bertoni) under Middle Egypt conditions. The experimental design was a split plot in three replicates and the main plot were devoted N fertilizer levels ( 40, 60 and 80 kg N fed^-1) while compost levels (0, 3 and 6 ton fed^-1) were allocated in the sub plot. The obtained results revealed that N fertilizer level and/or compost level had a significant effect on plant height (cm) , fresh and dry leaves weight (g plant^-1) , N, P& K contents of stevia leaves and N uptake kg fed^-1, dry leaves yield kg fed^-1 , stevioside (St %), rebaudioside A (Rb%), stevioside  yield (kg/fed) and rebaudioside A yield (kg fed^-1), the remained nutrients ( N,P & K (ppm) and OM % ) in the soil post-harvest of stevia  in two growing seasons, except P% of leaf in the 2^nd season for N fertilization. A significant interaction was scored between N fertilizer level and compost rate with regard to plant height (cm) , fresh and dry leaves weight (g plant^-1) , N % of stevia leaves and N uptake kg fed^-1 , dry leaves yield kg fed^-1 , stevioside  (St %), rebaudioside A (Rb%), stevioside  yield (kg fed^-1) and rebaudioside A yield (kg fed^-1) of steviain the two growing seasons. From the present study , it may be concluded that the application of  60 kg mineral N fertilizer + 6.0 ton compost fed^-1 was the best treatment for improving the yield and quality of stevia and is advisable to achieve the highest values of rebaudioside A (298.99 and 297.74 kg fed^-1) ,and net profit of stevia.