This study was carried out to modify an air-carrier sprayer as a pneumatic cotton picker to suite the small holdings area. The experiment was designed statistically as a split plots with three replicates. The main plots involved air suction pressure treatment levels of 0.31, 0.38, 0.82 and 0.91 kPa. While, the sub-plots were devoted for defoliant and boll opening spraying treatment levels of applying DROP Ultra + FINISH Pro 15-25 days prior and the bereaved of defoliant and boll opening. these treatments were compared with the manual picking method. The results indicated that the modified cotton picker accomplished higher performance than the manual method. Using the modified cotton picker at 0.91 kPa air suction pressure under defoliant and boll opening achieved the higher actual field capacity value of 14.69 kg/h, the higher picking efficiency value of 97% and the lower specific energy requirements of 19 kJ/kg. While, using the modified cotton picker at 0.31 kPa. air suction pressure under leaves drop accomplished the higher field efficiency values of 83% and the lower criterion costs value of 22.83 LE/h. whilst, there was not a significant difference between the modified cotton picker and the manual method due to the cotton fiber characteristics. Finally, it is recommended to apply the modified cotton picker, especially at 0.91 kPa. air suction pressure using leaves drop.