A field experiment was conducted in private farm Damietta governorate, Egypt to study the effect of zinc treatments (0.0, 0.2, 0.4, and 0.6%) as a foliar application and phosphorus fertilizer rates (0, 300 and 600g P2O5/plant) and their interaction on the growth, nutrient content and uptake of guava (Psidium Guajava L.) seedlings. Zinc treatments were added 4th times one month between every foliar application. Treatments were arranged in a split block design with three replicates. Plant height, stem diameter, leaves number/ plant, fresh and dry weight, N, P, K and zinc uptake were determined. All the previous parameters significantly were affected by phosphorus rates, zinc levels and their interactions. Obtained data show that the higher phosphorus rate (600 g P2O5/plant) recorded the highest values of all previous parameters except potassium uptake by seedlings leaves. In addition, the treatment of 0.6 % zinc gave the maximum values of zinc, potassium, phosphorus uptake, dry and fresh weight over the control treatment. These results may be due to low available phosphorus and zinc in soil. The highest nitrogen, phosphorus and potassium uptake values in both samples (after two and four months) were found at the treatment of 600 g P2O5/plant combined with 0.2% zinc. Finally, it concluded that using zinc as a foliar application and soil addition of phosphorus fertilizer rates improved guava seedlings growth and nutrients uptake.