The reliability on the groundwater wells in Wadi El-Natrun Region was determined in order to help in agricultural development plans for adding a new water resources and new agricultural land. Whereas, the data about the construction of 6 groundwater wells in this region, were studied analysis to focus on 6 main indicators of well production and cost of water extracting. Those indicators include the study aquifer variables as well storativity (s), ground water properties, well efficiency, transmissivity of aquifer (T) wells variables as radius of influence (R) and the hydraulic conductivity (K). In addition the total cost of pumping 1m³ water. Based on a surveying and collecting data, statistical and mathematical analyses were conducted for identifying these data. The gained results showed  the follows; the values of total dissolved solids (T.D.S) are ranging from 451 to 1000 mg l^-1 and the pH  are ranging from 6.70 to 8.22.Thus ,the extracted water found to be suitable for agricultural purposes and valid to irrigation  directly without any treatments. When applying mathematical equation for groundwater flow and selection equation to calculate well variables and aquifer has to follow that equations for unconfined aquifer due to the presence surface layer of clay that leads aquifer at that region is unconfined. The average total costs of well-constructed at a depth of (200 m) and a diameter of (250mm) were estimated about 298310 LE. However, the cost of pumping 10 ³m ³ water of the total amount water pumped by the well during the period of operation throughout his life were estimated about 28.91 L.E.