Laboratory experiments were carried out to study the degree of infestation by Sitophilus oryzae and Rhizopertha dominica on two wheat varieties, Sakha 8 and Sakha 92 priorly treated in the filed with bio-organo- fertilizers [Azotobacter inoculation (of grains) and/or farmyard manure (FYM) treatments (1% by weight)] under three levels of nitrogen fertilization (20%, 60% and 100% of recommended N dose, 70 kg N/fed), during 1997/98 and 1998/99 seasons.                 The obtained results showed that the degree of infestation and the mean of emerged adults of S. oryza affected by the variety of wheat grain. On the other side, wheat variety had no effect on the mentioned parameters of Rhizopertha dominica.                 There were significant effect on the degree of infestation and the number of progeny of both S. oryzae and R. dominica as a result of different levels of nitrogen fertilization and combination of bio-organofertilizers on both tested varieties of wheat, Sakha 8 and Sakha 92. R. dominica caused the highest infestation on both wheat varieties, comparing with S. oryzae.                 These findings show that the level and the kind of fertilizer had some effect on the degree of infestation and number of progeny of the two tested insects for the two used wheat varieties. Further studies are needed to assure these findings.