The present work was carried out at three locations in Kafr
El-Sheikh governorate during 2000 to study the efficiency of the fungus, Beauveria bassiana against the insect pests infesting honey bee combs or associated with them namely, Galleria mellonella L., Achroia greisella L., Ephestia sp., Tribolium confusum Du Val., T. castaneum (Herbst.), Cassida vittata de Villers, Hypera brunneipennis Boh., Sitona lividipes, Gryllus burdigaiensis and Oxycarinus hyalinipennis Costa under laboratory and store conditions.The obtained results revealed that B. bassiana (1.6 x 108 conidia/ml) had the higher mortality percentage against larvae of G. mellonella, A. greisella, Ephestia sp. and adults of H. brunneipennis, S. lividipes, G. burdigainsis and O. hyalinipennis at 20 days after treatments recording 96, 96, 100, 96, 86, 52 and 80%, respectively, under laboratory conditions. Also, B. bassiana at the same concentration caused the highest mortality for these insects recording 82, 72, 82, 92, 78, 26 and 70%, respectively, under store conditions. On the other hand, B. bassiana had the lowest mortality percentage against T. confusum, T. castaneum and C. vittata recording 10, 18 and 10%, respectively under lab conditions, while the morality percentage under store conditions for these insects were 22, 38 and 14%, respectively. It could be stated that B. bassiana may be utilized as a biological agent for controlling of G. mellonella, A. greisella, H. brunneipennis, S. lividipes, G. burdigaiensis and O. hyalinipennis under store conditions.