Two field trials with 10 years old grapevines cv. Ruby seedless (highly susceptible cultivar) were conducted at Nobaryia region, Egypt. In these trials, treatments consisted of leaf removal, shoot removal, topping, (leaf removal, shoot removal and topping) and a nonmanaged control. An additional trial, compared the leaf removal treatment with nonmanaged control .All plots were established in a split –plot design with or without fungicides .The above mentioned treatments were applied during the growing season starting at full bloom till veraison stage (the beginning of ripening) in order to control botrytis bunch rot. The obtained results showed that the disease incidence and severity of botrytis bunch rot was best reduced by using any of the used canopy management treatments compared with the nonmanaged control. But, the greatest reduction in incidence and severity occurred in the treatment with leaf removal + shoot removal and topping. In additional trial, leaf removal also reduced disease incidence and severity in nonsprayed control compared with the in tact nonsprayed control.The greatest reduction in incidence and severity was in the treatments with three sprays of fungicide (Euparen M) at bloom, pre-close and veraison. Also, the produced fruit yield from treated vines was significantly higher during the first and the second seasons in comparison with that of untreated vines.