Amino and fatty aCld contents in leaves of two local globe artichoke cultivars (Cordoon and I-lybride c vs ‘) were estimated in response to infestation With certain piercing sucking insect pests , l included five aphid speCies . in addition to Semis/a taoaci Genn. Empoascae decipiens Paoli and Thrips tabaci L The aphid populations ( included .4. . febae L , A. gossypli Glov . . .i‘ttacrosiphum euphorbiae l T ifvfg/zus persicae (Sulzer }. M. so/anif Kalt )were the highest number on globe artichoke leaves of both cultzvars during the tested seasons . followed oy S. tabaci adults , while E . decici'ens and T. tabec; populations were The lowest ones. Amino and fatty aCids in plant leaves were isolated and identified the percent measurements of its fractions for infested arc uninfeszed leaves were estimated ard effect of these infestations on the content of amino and fatty acids in plant leaves were discussed , 17 amino acids , to fatty aCids were isolated frcrn two local globe artichoke cullivars ; Cordoon and Hybride cv 3. Chemical anaIySis showed that infestation caused a deficiency in some essential and non- essential aCids . as welt as in fatty aCids concentrations Recorded decreases in some analyzed amino aCids ranged in infested leaf samples between 5.21- 46 5 9‘0 and 4 8 — 33 3 9'5, whle ranged in some fatty acids: 149-766% and 4.3-8? 5%. respectively in the two tested cultivars . A complete reduction (lOOS'b) appeared affected these infestations, in both 2 fatty acids; Caprylic and Trydecylic ir Cordoon cv., and 4 fatty acids , the two tater, Margaric, X 2 in Hybride cv. Also, an increase showed, in some of this amino aCIdS concentrations in infested leaves, where it ranged in some of both essential and non- essential amino acids ZOE-696% and 3.75 - 68 1%, while ranged in fatty acids 51-677% and 18 7- 92 80.0 respectively in the two tested ccltivars. when compared With those of uninfested leaves samples Great increase in some amino and fatty acids break-out iri infested leaves sample, acted in Proline 138 2%, in two fatty acids. Undecylic (500%) and Ricinoieic (205,836) each in Hybride cv., no changes were recorded in Histidine in Cordoon and in Lauric fatty acid in Hybride cv