The relative susceptibility of secound and fourth instar larvae of Phthorimea operculelfa (Zeller) to botanieal extrasts of Mali azedanch l... Chinaberry fruits , Ajuga mpponeratic , Zygophyfum spp. and . Granulosis virus (GV) was studied by bioassay laboratory condition. Larval mortality increased with increasing the doses . LC50 values were 0.266- 3.851- 15.23 and 2.111 for the fourth instar larvae of Mali azedarch L, Chinaberry fruits , Ajuga mpponerafic , Zygophylum ,respecfively . LC50 values were 1.905 - 3.?14 - 15.23 and 1.9?? for the second instar larvae of Mali azedarch L, Chinaberry fruits , Ajuga mpponerafic , Zygophylum spp. respectively . LC50 values was 0.490 for (GV) fourth instar larvae of Granulosis virus . On the other hand L050 values was 1.9?? for secound larval instar larvae of Granulosis virus (GV) .The bioinsecticide . Granulosis virus (GV) and botanical extract Zygophylum simplex were the most toxic. Percent Iaraval mortality and that of larvae which failed to pupate increased by increasing the concentrations . While percent pupation and that of emerged adults decreased by increasing the concentrations of the different treatments. Morphological deformities were observed during pupae stage and adults produced from the survived treated larvae .