Biological and phytochemical studies were conducted onSuadea vermiculata to investigate the biologically active compounds of this plant against Aphis caraccivora Koch. Results showed that, fraction C with LC₅₀ 0.081 mg/cm² and LC₉₅ 0.226 mg/cm² was the most effective compared with the crude extractLC₅₀ 0.104 mg/cm² and LC951.338 mg/cm² followed by fraction A (LC₅₀ 0.103 mg/cm² and LC₉₅ 0.352 mg/cm² ) and then fraction B which had the lowest LC₉₅ value (0.709) than those of crude extract (1.338). Data also indicated that these fractions composed mainly of fatty acids, fatty acids methyl esters in addition to hydrocarbons. The main active component of fraction A, fatty acids methyl esters with percent area 70.698 % followed by 22.452 % monoterpenes, lenoleic acid with percent area 2.692 and low amount of hydrocabons with area percent 0.745. As regarding fraction B hydrocarbons represented the main components with percent area 56.425 %. The other compounds identified in this fraction were fatty acids 14.066 %, methyl anthranilate 15.706 % and methyl salicylate 7.650 %. Fraction C was the highest toxic fraction against A. craccivora, its chemical constituents were fatty acids methyl esters with 15.717 %, fatty acids 10.063 % and monoterpens 7.991 %. Methyl salicylate identified in this fraction with area percent 4.539 in addition to 15.470 % hydrocarbons.