Studies were conducted to determine rate of resistance development in laboratory strain of Rhizoglyphus robini to five compounds namely; Damaseisa, Vertmic, Bio – Fly, Neemix and Endo. The susceptibility of the mites to tested compounds was assessed every generation during the period of selection to determine the effect of selection on the resulting generations. The rates of resistance development of Rhizoglyphus robini during nine generations of selection with Damaseisa;Vertmic; Bio-Fly; Neemix and Endo. The resistance ratios of the R. robini individual's during the generation of selection varied in their tolerant against the different compounds under laboratory condition.