The insecticidal activity of the plant Calotropis procera against the insect pest Tribolium castaneum was tested by using leave extract of the plant. Leaves were collected in the vegetative stage and were air dried, ground and stored until extraction. In the preliminary investigation, n-Hexane was found to be the most active with a mortality of 40% followed by methanol and acetone (30 %) each. However, the water extract was found to be the least active among all extracts. Fractionation with n-Hexane, Heptane, ethyl acetate, and chloroform was performed in order to gets the more purified fraction containing the active constituent. Heptane, fraction found to be the most active in terms of mortality percentage (70%) followed by n-Hexane, Chloroform and Ethyl acetate respectively. Adults of Tribolium castaneum. were used for bioassay and Soxlet method was used for extraction to get more extracts. Leaves only were used for extraction since they produced more extracts than flower and root.