Cereals especially wheat grains are an important food source for the majority of the world population. Safe grain storage methods are thus of fundamental importance to ensure food supply from harvest to the next years. Consequently, the current study aimed to investigate the effect of non-customary application, seven color agents namely, brown chocolate, agricultural green, ponceau 4R., sunset yellow (FCF), tartrazine, titanium dioxide, and brilliant blue FCF on Tribolium castaneum, Sitophilus oryzae and Trogoderma granarium through measuring some of parameters: % mortality, effect on F₁ progeny, % weight loss and % germination compared to pirimiphos-methyl (as control). Results obtained indicated that percent of mortality for S. oryzae was between (13-58%) after 7 days which increased to (26.7-71.7%) after 12 days with the all tested coloring agents. Brilliant blue dye had the highest influence with LC₅₀ values of 4.71 and 2.25% w/w after 7, 12 days, respectively. While, tartazine dye achieved the lowest action with LC₅₀ values of 9.07 and 5.93% w/w at the same periods. For T. castaneum titanium dioxide had the highest impact with LC₅₀ of 7.9 and 4.4% w/w, T. granarium had the highest response to brilliant blue (FCF) with LC₅₀ of 5.24 and 1.1% w/w, after 7 and 12 days, respectively. The tested coloring agents reduced the population and reduced the percent weight loss compared to control. Eventually, the current study suggest using the tested colors as alternative control methods, however further studies to ensure their safety, as food additives, are needed.