The suitability of the three major provinces, (Bir El-Abd, El-Arish and Sheikh Zoweid) of north Sinai governorate for establishing and propagating of honeybee colonies was evaluated for two successive years, (2019& 2020). Colonies established in regions of Sheikh Zoweid and Bir El-Abd attained significant progression in all biological and productive evaluated activities than those presented at El-Arish. The rates or percentages of increase in the mean values of two combined years of different activities were 65.3 % & 48.7 % in worker brood production; 183.1 % & 136.8 % in drone brood production; 28.5 times  & 8.3 times in queen cells construction;  54 % & 25.4 % in the number of adult worker population; 2.3 times & 1.2 times in the quantity of stored pollen and  4.5times & 4.3 times in honey production for colonies located at Shiekh Zoweid and Bir El-Abd, than El-Arish,  respectively. Therefore, El- Shiekh Zoweid and Bir El-Abd to be considered more pronounce in the qualitative and quantitative of honeybee colonies than El-Arish province and could be included in the sustainable beekeeping programs in Egypt.