American bollworm, Helicoverpa armigera is the foremost insect that negatively affected cotton crops around the world. A field experiment was conducted at the Sedi-Salem area, Kafr El-Sheikh Governorate,Egypt to assess the bioefficacy of emamectin benzoate 5 SG(EB)on cotton against H. armigera.The tested pesticides were used as a foliar application under field conditions at the2019-2020season.The experiment was designed in plots of 5 m × 5 m size using a randomized block design (RBD) with seven different treatments.A pneumatic knapsack sprayer was used for foliar application of tested pesticides. Three doses of EB @ 7, 11, and 15 g a.i./ha were evaluated against the pest under study. Furthermore, endosulfan 35 EC, Proclaim^®, Spinosad 45 SC, and an untreated blank were also included in the field experiment. The findings concluded that 11 g a.i./ha of EB was the active dose for controlling the larval population of H. armigera.This dose caused a 64.75% reduction of boll damageover an untreated check at the end of observation in the field experiment.The yield ranged from 16.00 to 19.66 q/ha in all treatments.EB at 15 g a.i./ha was a very effective dose which was on par with the final results of 11 g a.i./ha.Entirely EB treatments augmented seed cotton yield under field conditions as compared to the control plot. The study demonstrates the potentiality of EB as an eco-friendly bioinsecticide against the American bollworm.The effective doses of EB @ 11and 15 g a.i./ha should be used in the cotton field to manage the infestation of H. armigera.