The present study, lab and field work was conducted to evaluation of toxic-effect and bio-activity of some newly conventional-pesticides (challenger, oberon, lambda, lant, neem oil and eucalyptus oil) to control of females-adult and stages of eggs for two spotted spider mite T. urticae. Addition to, evaluation of side-effects of sub-lethal dose of tested-chemicals on some biology aspects of spider mite T. urticae, and evaluates of compounds toxicity tested pest invested cotton-plants in fields.In laboratory andfield the results showed that, challenger gave high toxicity to eggs-stages and adult-females of tested pest. The result indicated that, eucalyptus oil and neem oil were the least compound. Challenger and oberon are the most effective compounds tested on egg deposition and the same effective challenger and oberon were the most effective compounds against the motile stages, while lant was of moderate effect of T. urticae. Eucalyptus oil and neem-oil gave lower effects to motile-stages of the tested pest. Challenger and oberon exhibited the best results in this respect. All compounds successes in population-density reduction of motile-stages of spider mite, T. urticae in lab and field-experiments during the two seasons 2019-2020.