The Khabra grain beetle, Trogoderma granarium Everts is one of the serious primary insect pests attacking the stored wheat grains. The insect pest was reared on four wheat varieties to study their effects on the biological aspects as the immature stages, the ovipositional periods and the total number of egg-laying per the female. Giza 171 wheat variety showed a shortest duration of the larval stage and presented by 21.4 ± 0.4 days. Also, the shortest duration of the pupal stage was recorded at Giza 171 or Masir 2 wheat varieties and presented by 4.1 ± 0.2 days. The shortest oviposition period was recorded when reared the insect at Sakha 94 and presented by 10.5 ± 0.7 days. The wheat variety Giza 171 has to be considered the most favorable variety for T. granarium and gave the shortest development for immature stages (29.2 days), the highest oviposition (57.4 eggs/female), and the highest survival rate during the larval and pupal stage (96.0 %).