The high economic costs of agricultural production, especially with the high prices of nematicides, have led many researchers to find alternative strategy management to the root-knot nematode. The current study aimed to evaluate the effect of some commercial pre-plant incorporated herbicides; Benefin, Cobex, Devrinol, Prefar and Treflan as nonspecific treatment as a part of strategy of integrated pest management on the root-knot nematode, Meloidogyne javanica infesting cucumber plants in commercial open fields conditions. All the tested pre-plant incorporated herbicides caused a significant reduction in the root-knot nematode criteria with varying degrees compared with the control. The treatments by Treflan showed the highest effect on the reduction percentage of root-knot nematode (75.8%, 81.8% and 77.4%) in descending three tested rates through the progress of the plants growth, followed by other treatments down to at the least effect associated with Prefar at double rate treatment (40.1%). In conclusion, in the case of the need to weeds control preferred pre-plant herbicides, especially Treflan , Benefin and Devrinol where it has a side effects on decreasing the population of the root-knot nematode.