The tomato and cotton whitefly, Bemisia tabaci (Gennadius) Biotype “Q"  (Hemiptera: Aleyrodidae) is an important pest on cucumber. The present work deals with the efficacy of the compounds, Mineral oil, Jojoba oil , Sulphur, Peacilomyces fumosoroseus, Azdrachtin, Verticellium lecanii and Actara on B. tabaci Biotype “Q"   and its parasitoid,  Eretmocerus mundus (Mercet) (Hymenoptera : Aphelinidae) and predator, Chrysoperla carnea  (Stephens)  (Neuroptera: Chrysopidae).  Field experiments were carried out to evaluate of the seven compounds on B. tabaci Biotype “Q"   and associated natural enemies (E. mundus and C. carnea ) on cucumber  crop at Dakahliya Governorate.  When the numbers of whitefly and its parasitoid and predator were high during October.  The results indicated that the four compounds Jojoba oil , Peacilomyces fumosoroseus, Azdrachtin and Verticellium lecaniigave moderate effect against B. tabaci Biotype “Q"   (59.3-66.7 and 58.7-66.3%),  the parasitoid, E. mundus (59.9-66.7%) and the predator, C. carnea (60.3-67.7 and 60.3-67.3%) during the two years under consideration, respectively. On the other hand, Actara gave high efficacy against B. tabaci Biotype “Q"   ( 85.2 and 87.0%), C. carnea  (86.3 and 85.0 %) and on E. mundus ( 85.0 and 88.3%) . While, Mineral oil and Sulphur compounds gave 79.2 & 72.6 and 79.9-70.9 % for B. tabaci; 78.1 & 71.7 % and 78.2 & 72.2 for  E. mundus and 78.1 & 72.5 % and 78.9 & 72.5 for  C. carnea mortality during the two years under consideration, respectively. It is concluded that the use of certain botanical extracts (Azdrachtin ) and fungi (Peacilomyces fumosoroseus and Verticellium lecanii )for the control tomato and cotton whitefly, B. tabaci Biotype “Q" is an important and useful approach. As well as using these compounds  safely   effect of natural enemies and environment.