The role of pollen and/or bee bread availability was evaluated on brood rearing, protein content and haemolymph of 6-days-old larvae worker honeybees. The highest area of stored pollen and/or bee bread and worker unsealed brood was recorded during August with an average 157.7±24.701 and 347.7±51.348 (sq. inch / Colony), respectively. Highly significant positive correlation was detected between stored pollen and/or bee bread and worker unsealed brood (r = 0.902**). Physiological studies on larvae and their haemolymph indicated that the, lowest protein content of both larvae and their haemolymph 22.03±6.325 % and 4.04±0.48 (µg/µl), respectively was found during April. Significant positive correlation was noticed between stored pollen and/or bee bread from one side and both larval protein content and haemolymph protein content on the other hand, (r = 0.393* and 0.345*), respectively. The highest of both total soluble solids (TSS %) and total haemocyte count (THC) was found during May and January. On the other hand, the lowest average of both (TSS %) and (THC) was noticed during April. Differential haemocytes counts (DHC) were counted in smears of their haemolymph. There were significant differences in different haemocyte types among various months. So, it turns out previously, it can be recommended for special attention protein nutrition artificially by providing nutrition supplements or pollen substitutes for bee colonies and that in periods of scarcity or lack of pollen as well as in the periods of disease spreads. In this process the chances of incidence of disease can be reduced and improve the immune system of bees. This is in addition to reducing the loss incident in bee colonies as a result of starvation.