The effect of Abamectin and D-limonene was evaluated against desert locust nymphs under laboratory and field conditions, as well as the combined effect of both insecticides with the fungus Metarhizium anisopliae var. acridum, also the stability of Abamectin and D-limonene was assessed under different enveronmental condition. The obtained results revealed that both Abamectin and D-limonene could be used to control desert locust, where the reduction in 5th nymphal instar under the laboratory condition reached to 67.5 % after three days post treatment with 40% Abamectine. Whereas under field condition the reduction among young nymphs three days post treatment were 83.33 and 66.66 % in case of 40 % Abamectin and D- limonene, respectively. Moreover the combined effect of 10% Abamectin or D- limonene with M. anisopliae var. acridum caused significant increase in the toxic effect of the fungi, reached to 58.33 and 51.66 % , respectively.