Stripe rust, caused by Puccinia striiformis f. sp. Tritici [Pst], is an important wheat disease that causes considerable yield losses in wheat growing areas worldwide. It is better to control the disease throughout the use of cultivars with durable resistance. This study to evaluate 20 Egyptian cultivars against stripe rust at both seedling and adult stages, at a rust hot spot location in Sakha Agriculture Research Station, Egypt, during the 2010/2011 and 2011/2012 growing seasons. Slow rusting resistance at adult plant stage was assessed through the determination of infection type (IT), disease severity (DS), relative area under disease progressive curve (rAUDPC), and coefficient of infection (CI). Results indicated that the among 20 cultivars tested, five cultivars showed resistance reaction i.e. Misr 1, Gemmeiza 10, Gemmeiza 11, Sids 13 and Sohag 3, while the remained tested cultivars showed susceptible reaction at seedling stage. On the other hand, at adult plant stage five Egyptian cultivars showed little or no infection, therefore it were selected as immune or resistant cultivars. i.e. Sakha 61, Gemmeiza 10, Benisweif 4, Benisweif 5, and Sohag 3, while the rest cultivars tested showed moderately resistance to moderately susceptible and susceptible reaction. The cultivars Giza 168, Sakha 94, and Gemmeiza 7 had the susceptible reaction at seedling stage and it were moderately resistant to moderately susceptible at adult stage. Consequently, these cultivars with low rAUDPC (7.14 to 14.28%) most probably could have slow rusting resistance. Results of mean comparison values of CI and rAUDPC indicated that Giza167, Gemmeiza 5, and Sids 1 exhibited the highest CI and rAUDPC. Correlation analysis of different parameters also showed highly strong relationship of CI with rAUDPC and disease severity (R2 = 0.92 and 0.94, respectively). Meanwhile, the thousand kernel and test weight decreased due to high rust infection, high significant difference could be detected among cultivars. As for 1000 kernel weight the highest value was recorded with Beniswief 5 (53.90g and 50.20g) during 2010/2011 and 2011/2012, respectively. Regarding the test weight Misr 1 was the least affected cultivar by the disease that reduced by 1.52 %, at first season while Beniswief 1 recorded 1.57% in the second season.