The experiments were conducted in Plant Protection Research Institute, Sharkia branch, Agriculture Research Center to study the toxic and biological effects of phenol compound against the pink, spiny and American bollworms under controlled conditions of (26 ± 1 C° and 70 ± 5 % R. H.). Data revealed that phenol compound had highly toxic effect on the eggs of the spiny followed by pink then American bollworms, but the highest toxic effect against newly hatched larvae attained against the American followed by pink then spiny bollworms larvae. On the other hand,  the latent effects of the phenol compound on the three insect species were presented in increasing the accumulated mortality of larval and pupal mortality  percentages, non significant increasing on  larval duration of the three cotton bollworms insects, and significantly decreased in larval  and pupal weight, increasing pre and post-oviposition periods, decreasing oviposition periods, male and female longevities and also reduced fecundity, while the highest reduction in laid eggs recorded on pink followed by American  then spiny bollworms compared with untreated control, while the hatchability percentages decreased significantly with pink bollworm and non significant with spiny and American bollworms compared with untreated control.